Inherited Prostate Cancer
Prostate cancer is well known to have a strong family risk, yet the genes that cause it are still largely unknown. Fund research that helps every family at increased lifetime risk for cancer.
Identifying High-Penetrance Prostate Cancer Risk Genes to Improve Precision Medicine and Precision Screening for Families
Family history is well-established as a risk factor for development of prostate cancer but scientists currently lack a comprehensive understanding of underlying genetic causes.
The Prostate Cancer Foundation is supporting research to identify inherited genes that confer a high risk of developing prostate cancer not just for men but also for their sons and daughters.
These include the same BRCA genes implicated in families with frequent occurrence of breast and ovarian cancer.
These studies will identify specific high-risk genes, identify precision medicine treatments for patients who carry these genes, develop genetic testing and genetic counseling paradigms to identify family members who are also carriers, and develop protocols for enhanced screening in carriers not yet known to have prostate cancer.